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reduceModel

reduceModel[model]
performs FVA on provided model and removes reactions that cannot carry steady-state flux.
reduceModel[model, constraints]
additional constraints can be provided (that take precedence over the constraints in the model)
  • Appropriate options can be passed down to fva.
EXAMPLESCLOSE ALL
Basic Examples   (1)
All exchange fluxes are closed towards the inside
Reducing the initial model reveals that only two reactions can carry steady-state flux
Simulating a glucose minimal mediun under aerobic conditions
Reducing the modified model reveals that 87 (out of 98) reaction can carry steadty-state flux
The 11 removed reactions correspond to the other 5 potential carbon sources in the model
Additional constraints can be provided
In[1]:=
Click for copyable input
In[2]:=
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All exchange fluxes are closed towards the inside
In[3]:=
Click for copyable input
Out[3]=
Reducing the initial model reveals that only two reactions can carry steady-state flux
In[4]:=
Click for copyable input
Out[4]=
Simulating a glucose minimal mediun under aerobic conditions
In[5]:=
Click for copyable input
Reducing the modified model reveals that 87 (out of 98) reaction can carry steadty-state flux
In[6]:=
Click for copyable input
Out[6]=
Out[6]//Short=
The 11 removed reactions correspond to the other 5 potential carbon sources in the model
In[7]:=
Click for copyable input
Out[7]=
Additional constraints can be provided
In[8]:=
Click for copyable input
Out[8]=