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0.25.0

by The COBRApy Team


Release notes for cobrapy 0.25.0

New features

  • Add knock_out_model_genes to simulate knock-outs, setting reaction bounds of affected reactions to zero and returning a list of reactions that were knocked-out. Replaces delete_model_genes and undelete_model_genes since it is context sensitive.
  • Improve reading of matlab models which will include metabolite and reaction annotations.

Fixes

  • model.copy() will now correctly copy GPRs.
  • Fix an error where matlab models can not be read if their bounds exceed the configuration default in some cases.
  • Fixed some bugs in GPR().from_string() where it was using the unmodified string, leading to errors with GPRs that should work. Made GPRs that have empty parenthesis fail more comprehensibly.

Other

  • Move tests to a different directory, from src/cobra/test to tests (#1191).
  • Add two tests for GPR fixes:
    • test_gpr_wrong_input()
    • test_gpr_that_needs_two_replacements()
  • Clean up Python syntax (#1152, #1153, #1171, #1173, #1182)

Deprecated features

  • Deprecate delete_model_genes, undelete_model_genes

Backwards incompatible changes

  • Remove find_gene_knockout_reactions from delete.py
  • Remove _find_gene_knockout_reactions_fast, _gene_knockout_computation, _get_removed from test_delete.py
  • Remove pymatlib direct transfer of models to matlab process. Please use save_matlab_model() and then read the model in matlab.