Inactivegenedeletion¶
- deleteInactiveGenes(model, trData, trDataPath, thApproach, lowerTh, upperTh, sheetIndex, growthNotAffectingGeneDel, percentile)[source]¶
Returns a tissue specific model with inactive genes deleted
- USAGE
model = deleteInactiveGenes (model, trData, trDataPath, thApproach, lowerTh, upperTh, sheetIndex, growthNotAffectingGeneDel, percentile)
- INPUTS
model – model strusture
trData – table with columns ‘GeneId’ and ‘Data’
trDataPath – char full transcriptomics data filename
thApproach – double (1-GT1, 2-LT1, 3-LT2)
lowerTh – double
upperTh – double (required for LT2)
sheetIndex – double transcriptomics dataset sheet index
growthNotAffectingGeneDel – double (1 or 0) check if grRatio equals 1 after gene deletion compared to wildtype
percentile – double (1 or 0) bool option to convert thresholds to percentile value
- OUTPUTS
model – extracted model